Biphasic model of cartilage
WebThe zone of calcified cartilage is the mineralized region of articular cartilage that anchors the hyaline cartilage to the subchondral bone and serves to disperse mechanical forces … WebPrevious studies have shown that stress relaxation behavior of calf ulnar growth plate and chondroepiphysis cartilage can be described by a linear transverse isotropic biphasic model. The model provides a good fit to the observed unconfined compression transients when the out-of-plane Poisson's ratio is set to zero.
Biphasic model of cartilage
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WebJan 1, 2014 · The conewise model was later combined with the biphasic poroviscoelastic model in order to capture load responses of unconfined compression and uniaxial tension simultaneously (Huang et al., 2001). The triphasic and biphasic models predict almost the same equilibrium responses (Ateshian et al., 2004). The reason for that is the … WebApr 24, 2024 · The relative scarcity of 3-D constitutive models of cartilage speaks to the challenges of capturing the tissue’s complex behavior in a computation model. Existing 3-D, large-strain FE models of articular cartilage use single-phase (e.g., [31, 87, 88]), biphasic, and multi-phasic models, some at considerable computational cost.
WebNov 25, 2011 · The biphasic model is the most traditional model of articular cartilage and other fluid-saturated tissue which takes the interstitial fluid movement into account (Mow … WebApr 14, 2024 · There are several constitutive material models in the literature that can characterize cartilage mechanics in different loading scenarios. Briefly, traditional …
WebThe accumulation of MMPs in osteoarthritic cartilage may have a role in the biphasic progression of OA-related pain. Temporal association of changes in ECS and MMPs expression shows a potential therapeutic approach that utilizes the concept of combining indirect ECS-mediated MMP inhibition and ECS modulation of pain transduction. WebApr 21, 2009 · In particular, this model can predict the transition of Poisson’s ratio from very low values in compression (∼ 0.02) to very high values in tension (∼ 2.0) . Most of these phenomena cannot be explained when using only three orthogonal fiber bundles to describe the tissue matrix, a common modeling assumption used to date.
WebMay 30, 2014 · The cartilage layer is an inhomogeneous fibre-reinforced structure. 4,15,16 Previous studies using models of cylindrical cartilage sections have demonstrated that the constitutive relationship proposed by Ateshian’s group, in which the tensile and compressive behaviour are different, captures the mechanical performance of the tissue more ...
WebJan 1, 1987 · A mathematical solution has been obtained for the indentation creep and stress-relaxation behavior of articular cartilage where the tissue is modeled as a layer of … fear of clusters of thingsWebPlotting Biphasic Creep in MATLAB. As a precursor to doing the optimization in MATLAB, we will again perform a plot of the solution for the given parameters. From the Soltz and Athesian paper we have the following constants: h = 0.81mm. HA = 0.97 MPa or N/mm^2. K0 = 2.9 x 10^-16 m^4/Ns or 2.9x10^-4mm^4/Ns. PA=-0.06MPa. deb cutler tweed headsWebApr 14, 2024 · 5 Using Models to Investigate Pathways to Cartilage Failure. Synovial joint lubrication is one of the key roles of articular cartilage. Synovial joints can experience very small frictional force, with initial friction coefficient ranging from 0.005 to 0.02, while bearing extremely large mechanical stress [ 41, 42 ]. deb cutan foaming hand sanitiserWebCartilage tissue engineering is emerging as a promising treatment for osteoarthritis, and the field has progressed toward utilizing large animal models for proof of concept and … fear of clutter phobiaWebvations suggest that cartilage behaves like a sponge, albeit one that does not allow fluid to flow through it easily. Recognizing that fluid flow and deformation are interde-pendent has led to the modeling of cartilage as a mixture of fluid and solid components [59–61]. This is referred to as the biphasic model of cartilage. In this modeling ... deb cutan foam hand sanitiserWebApr 28, 2024 · Articular cartilage (AC) in the hip is a remarkable connective tissue that facilitates joint movement. Biomechanically, the AC is a unique biphasic material mainly … fear of clusters of small holesfear of cold calling