Niemi m. clin pharmacol ther. 2010 87:130-3

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WebbClin Pharmacol Ther. 2010;87(1):52–56. 67. Becker ML, Visser LE, Trienekens PH, Hofman A, van Schaik RH, Stricker BH. Cytochrome P450 2C9 *2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus. Clin Pharmacol Ther. 2008;83(2):288–292. 68. Webb1 jan. 2010 · Genetically impaired adenosine triphosphate‐binding cassette G2 transporter efflux activity results in a marked increase in systemic exposure to various statins, …

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WebbISSN 1819-9496 (Print) ISSN 2500-0136 (Online) Вход/Регистрация. О журнале WebbContributions of genetic variations in drug-metabolizing enzymes and transporter proteins to the inter-individual variation of rifamycins pharmacokinetics. shoring rental pa

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Webb19 maj 2024 · Niemi M, Neuvonen M, Juntti-Patinen L, et al.: Effect of fluconazole on the pharmacokinetics and pharmacodynamics of nateglinide. Clin Pharmacol Ther 2003; 74: 25–31 CrossRef 11. Webb7 juli 2016 · For this reason, starting in 2010, contemporary DDI guidelines from the US Food and Drug Administration and European Medicines Agency have included evaluation of key drug transporters, in addition to metabolizing enzymes, in characterization of victim and perpetrator DDI potential for new molecular entities in drug development. 7-9 … WebbSLCO1B1 • SLCO1B1 stands for solute carrier organic anion transporter family member 1B1 • SLCO1B1. is a gene located on chromosome 12, that encodes for an organic … shoring required depth

SLCO1B1 decreased function (Concept Id: C4545418) - National …

SLCO1B1 and ABCB1 variants synergistically influence the …

Webb19 okt. 2024 · In, 32 clarithromycin at concentrations of 10 and 100 µM led to reductions of 36% and 76%, respectively, in intracellular accumulation of pravastatin in human … Webb27 maj 2011 · Clin. Pharmacol. Ther. 87(1),130–133 (2010).Crossref, Medline, CAS, Google Scholar; 143 Tirona RG, Leake BF, Merino G, Kim RB: Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European– and African–Americans. J. Biol. shoring rentals edmontonWebbAt the same time, Huang et al. also found that ATP dramatically stimulated absorption of rosuvastatin in CRP-expressing MXR-M-VT membranes, with an apparent K m of 10.8 ± 1.1μmol/L at a high affinity site and 307 ± 89.4 μmol/L at a low affinity site, which strongly indicated that rosuvastatin also was the substrate of BCRP . sandwiches for potluck

"WebbNeuvonen M, Tornio A, Hirvensalo P, Backman JT, Niemi M Clin Pharmacol Ther 2024 Dec;110(6):1622-1632. Epub 2024 Oct 15 doi: 10.1002/cpt.2429. PMID: 34580865 Free PMC Article. Insights into the diagnosis of hepatocellular carcinomas … " - Niemi m. clin pharmacol ther. 2010 87:130-3

Niemi m. clin pharmacol ther. 2010 87:130-3

Transporter Pharmacogenetics and Statin Toxicity

Webb15 sep. 2010 · Author for correspondence: Mikko Niemi, Department of Clinical Pharmacology, Helsinki University Central Hospital, PO Box 705, FI-00029 HUS, … WebbClin Ther. 2010 Mar; 32(3):534-42. Sun H, Frassetto LA, Huang Y, Benet LZ. Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease. Clin Pharmacol Ther. 2010 Apr; 87(4):465-72. Grillo MP, Wait JC, Tadano Lohr M, Khera S, Benet LZ.

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Webb2010 - Volume 87 - 88; 2000 - 2009. 2009 - Volume 85 - 86; 2008 - Volume 83 - 84; 2007 - Volume 81 - 82; 2006 - Volume 79 - 80; 2005 - Volume 77 - 78; 2004 - Volume 75 - 76; … WebbClin Pharmacol Ther. 2010; 87(1):130-3 (ISSN: 1532-6535) Niemi M. Polymorphisms in transporter genes can have profound effects on statin pharmacokinetics. In particular, a …

Webb15 aug. 2024 · Introduction: Atorvastatin exhibits wide interindividual variability in treatment response, limiting the drug efficacy in coronary artery disease patients. Aim: To study the effect of genetic variants involved in atorvastatin transport/metabolism and correlate their lipid-lowering efficacy. Materials & methods: Genotyping was performed using 5′ … Webb12 juli 2024 · Jan H.M. Schellens. Department of Medical Oncology and Clinical Pharmacology, The Netherlands Cancer Institute – Antoni van Leeuwenhoek, Amsterdam, The Netherlands. Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. Search for more papers by this author

WebbAccording to available information, montelukast is metabolized by cytochrome P450 (CYP) 3A4 and 2C9. In order to study the significance of CYP2C8 in the pharmacokinetics of … WebbClin Pharmacol Ther. 2010; 87(1):130-3 (ISSN: 1532-6535) Niemi M. Polymorphisms in transporter genes can have profound effects on statin pharmacokinetics. In particular, a common genetic variant of organic anion-transporting polypeptide 1B1 reduces the hepatic uptake of many statins, increasing the risk of statin-induced myopathy.

WebbNiemi M (2010) Transporter pharmacogenetics and statin toxicity. Clin Pharmacol Ther 87(1):130–133. CrossRef PubMed CAS Google Scholar Niemi M, Leathart JB, …

WebbNeuvonen M, Tornio A, Hirvensalo P, Backman JT, Niemi M Clin Pharmacol Ther 2024 Dec;110(6):1622-1632. Epub 2024 Oct 15 doi: 10.1002/cpt.2429. PMID: 34580865 … shoring repairWebb13 dec. 2024 · Barn og ungdom (10-17 år): Heterozygot familiær hyperkolesterolemi: Anbefalt startdose 10 mg/dag som enkeltdose om kvelden hos gutter Tanner stadium II eller høyere, og jenter som er minst 1 år etter menarche. Anbefalt doseringsområde 10-40 mg/dag. Maks. anbefalt dose: 40 mg/dag. sandwiches for parties near meWebb15 sep. 2010 · About 15% of the oral nateglinide dose is excreted unchanged into urine. The CYP2C8*3 allele has been associated with decreased plasma concentrations of … sandwiches for parties odessa txWebb65 Niemi M. Transporter pharmacogenetics and statin toxicity. Clin Pharmacol Ther 2010; 87: 130-133 ; 66 Barnes PM, Bloom B, Nahin RL. Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Rep 2008; 12: 1-23 ; 67 Helms S. Cancer prevention and therapeutics: Panax ginseng. sandwiches for ladies luncheonWebbStatins reduce cholesterol, prevent cardiovascular disease, and are among the most commonly prescribed medications in the world. Statin-associated musculoskeletal … sandwiches for office lunchWebb18 jan. 2024 · Clin. Pharmacol. Ther. 76(2), 167–77 (2004).Crossref, Medline, CAS, Google Scholar; 37. Son M, Kim Y, Lee D et al. Pharmacokinetic interaction between … sandwiches fort leeWebb13 maj 2024 · Therapeutic protein-drug interactions and implications for drug development. Many intrinsic and extrinsic factors can affect an individual patient's drug … sandwiches for pregnant women